AdipoGen Cyclopamine (5 mg)
Supplier: AdipoGen AGCN20028M005
Cyclopamine (5 mg), Adipogen Life Sciences. Chemical. CAS: 4449-51-8. Formula: C27H41NO2. MW: 411.6. Isolated from Veratrum californicum. Cell permeable steroidal alkaloid. Specific sonic hedgehog (Shh) signaling pathway inhibitor. Directly interacts/inhibits Smo (smoothened). Teratogenic and antitumor compound. Inhibits tumor cell growth and progression. Shows selective activity against Shh-dependent tumors. Blocks abnormal cell growth associated with oncogenic mutations of Ptch and Smo in fibroblasts. Arrests cell cycle at G0/G1. Apoptosis inducer.
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