Tocris™ CYM 5442 hydrochloride

Selective S1P1 receptor agonist

Manufacturer: Tocris™ 3601/10

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Catalog No. 36-011-0R

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For Research Use Only


    Inhibitors CYM 5442 hydrochloride
    Purity >98
    Molecular Weight 445.94
    Quantity 10mg
    Product Type CYM 5442 hydrochloride

    Potent and selective S1P1 agonist in vitro (EC50 = 1.35nM). Activates S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1. Induces acute lymphopenia in mice. Brain penetrant.

    • Chemical Name: 2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl amino) ethanol hydrochloride
    • Formula: C23H27N3O4.HCl
    • CAS Number: 1094042-01-9
    • Solubility: Soluble to 10mM in water and to 100mM in DMSO
    • Purity: >98

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