R&D Systems™ Recombinant Cynomolgus VISTA/B7-H5 Fc Chimera Protein, CF
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.
Manufacturer: R&D Systems™ 9408B7100
DescriptionMeasured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 0.6-3 μg/mL.
Ships at ambient temperature.
|>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.|
|Human embryonic kidney cell, HEK293-derived cynomolgus monkey VISTA/B7-H5/PD-1 H protein Cynomolgus Monkey VISTA/B7-H5 (Phe33-Ala194) (N-terminus) Accession # XP_005565644 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)|
|4632428N05Rik, B7H5, B7-H5, C10orf54|
|Reconstitute at 200 µg/mL in PBS.|
|Lyophilized from a 0.2 µm filtered solution in PBS.|
|M.W. (Observed): 62-71 kDa, reducing conditions; M.W. (theoretical): 45 kDa|
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.|
|<0.10 EU / 1 µg of the protein by the LAL method.|
|0.6 to 3μg/mL|
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