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R&D Systems™ Recombinant Cynomolgus VISTA/B7-H5 Fc Chimera Protein, CF

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Manufacturer:  R&D Systems™ 9408B7100

Catalog No. 94-08B-7100


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Description

Description

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 0.6-3 μg/mL.

Order Info

Ships at ambient temperature.

Specifications

Specifications

VISTA/B7-H5/PD-1 H
Bioactivity
64115
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Human embryonic kidney cell, HEK293-derived cynomolgus monkey VISTA/B7-H5/PD-1 H protein Cynomolgus Monkey VISTA/B7-H5 (Phe33-Ala194) (N-terminus) Accession # XP_005565644 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
RUO
4632428N05Rik, B7H5, B7-H5, C10orf54
Recombinant protein
Cynomolgus Monkey
Reconstitute at 200 µg/mL in PBS.
XP_005565644
Lyophilized from a 0.2 µm filtered solution in PBS.
M.W. (Observed): 62-71 kDa, reducing conditions; M.W. (theoretical): 45 kDa
100 µg
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
<0.10 EU / 1 µg of the protein by the LAL method.
0.6 to 3μg/mL
Unconjugated
Yes
SDS
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