CYP17A1 Monoclonal Antibody (OTI5G10), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA503415

Catalog No. 50-167-4316

Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Specifications

• Antigen: CYP17A1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P05093
• Gene Symbols: CYP17A1
• Immunogen: Full length human recombit protein of human CYP17A1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI5G10
• Conjugate: Unconjugated
• Gene: CYP17A1
• Gene Alias: CPT7, CYP17, P450C17, S17AH
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1586
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid