Invitrogen™ CYP21A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575270

Catalog No. PIPA575270

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in CYP21A2 gene cause congenital adrenal hyperplasia.

Specifications

• Antigen: CYP21A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CYP21A2
• Gene Alias: 21-OHase; CA21H; CAH1; CPS1; CYP21; CYP21A2; CYP21B; Cytochrome P450 21; cytochrome P450 family 21 subfamily A member 2; cytochrome P450 XXI; cytochrome P450, family 21, subfamily A, polypeptide 2; cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2; Cytochrome P-450c21; Cytochrome P450-C21; Cytochrome P450-C21B; P-450c21; P450-C21; P450c21B; P450-C21B; steroid 21 hydroxylase; steroid 21-hydroxylase; steroid 21-monooxygenase
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1589
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P08686
• Gene Symbols: CYP21A2
• Immunogen: Synthetic peptide corresponding to amino acids 141-190 of Human CYP21A2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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