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CYP27A1 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 191951AP

Catalog No. 50-173-2366


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Description

Description

CYP27A1 participates in the degradation of cholesterol to bile acids in both the classic and acidic pathways.[1] It is the initiating enzyme in the acidic pathway to bile acids, yielding oxysterols by introducing a hydroxyl group to the carbon at the 27 position in cholesterol. In the acidic pathway, it produces 27-hydroxycholesterol from cholesterol whereas in the classic or neutral pathway, it produces 3beta-hydroxy-5-cholestenoic acid.It is also involved in the metabolism of vitamin D3. While CYP27A1 is present in many different tissues, its function in these tissues is largely uncharacterized. In macrophages, 27-hydroxycholesterol generated by this enzyme may be helpful against the production of inflammatory factors associated with cardiovascular disease.
Specifications

Specifications

CYP27A1
0.49 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q02318
CP27, CTX, CYP27, CYP27A1, Cytochrome P 450C27/25, Cytochrome P450 27, Sterol 27 hydroxylase, Vitamin D(3) 25 hydroxylase
Rabbit
IgG
150 μL
-20°C
Primary
1593
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CYP27A1
Liquid
CYP27A1
CYP27A1 Fusion Protein Ag7746
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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