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CYP2C9 Mouse anti-Human, Clone: OTI2C8, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525748

Catalog No. PIMA525748


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Description

Description

The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP2C (CYPIIC) subfamily comprises a group of constitutively expressed genes, some phenobarbital-induced genes, and several genes associated with sex-specific expression. Originally, at least 7 genes were assigned to the CYP2C subfamily, which maps to human 10q24.1-q24.3 and mouse chromosome 19. Humans contain fewer genes in this cluster than do mice or rats. Four genes are arranged in the following order and orientation along human chromosome 10: RBP4, CYP2C18, CYP2C19/CYP2C9, and CYP2C8. The previsously identified CYP2C10 is an artifact of CYP2C9 and not a distinct isoform. All of the CYP2C proteins localize to the endoplasmic reticulum.
Specifications

Specifications

CYP2C9
Monoclonal
0.48 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P11712
CPC9, CYP2C, CYP2C10, MGC149605, MGC88320, P450IIC9
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1559
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI2C8
Unconjugated
CYP2C9
Liquid
CYP2C9
Full length human recombit protein of CYP2C9 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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