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CYP2D6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 178681AP

Catalog No. 50-173-1841


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Description

Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme ft.s substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

CYP2D6
0.35 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P10635
CPD6, CYP2D, CYP2D6, CYP2DL1, Cytochrome P450 2D6, P450 DB1, P450C2D, P450DB1
Rabbit
IgG
150 μL
-20°C
Primary
100418253, 1565, 171522
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CYP2D6
Liquid
Cyp2d4, CYP2D6, Cyp2d67-ps
CYP2D6 Fusion Protein Ag12351
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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