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Tocris Bioscience™ Cystamine dihydrochloride Available on GSA/VA Contract for Federal Government customers only.

Transglutaminase inhibitor; neuroprotective

Manufacturer:  Tocris Bioscience™ 4981/50

Catalog No. 49-815-0R


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Description

Description

Transglutaminase inhibitor. Attenuates cell death induced by 3-nitropropionic acid (Cat. No. 4849) in Huntington's disease (HD) striatal cells. Also decreases aggregated and cross-linked huntingtin in transfected cells, and increases brain levels of BDNF. Shown to extend survival and improve motor performance in transgenic HD mice. Neuroprotective.

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