Cytochromeb245alpha Mouse anti-Human, Janelia Fluor 646, Clone: CS9, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP140974JF646
DescriptionCytochromeb245alpha Monoclonal antibody specifically detects Cytochromeb245alpha in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.
|Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen|
|Cytochrome B245 solubilised in octyl-beta-gluycopyranoside|
|Protein G purified|
|Store at 4°C in the dark.|
|This antibody recognises the light chain of cytochrome B245, also known as p22phox, a subunit of the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase). NADPH oxidase is a membrane-bound enzyme complex in neutrophils that produces the superoxide anion (O2-) by transferring single electrons from NADPH inside the cell across the membrane and coupling them to molecular oxygen. Superoxide is used for the destruction of pathogens. Individuals with defects in NADPH oxidase suffer from chronic granulomatous disease, characterised by severe recurrent infections.|
|Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)|
|Janelia Fluor 646|
|50mM Sodium Borate with 0.05% Sodium Azide|
|cytochrome b light chain, Cytochrome b(558) alpha chain, cytochrome b(558) alpha-subunit, cytochrome b, alpha polypeptide, cytochrome b-245 light chain, cytochrome b-245, alpha polypeptide, Cytochrome b558 subunit alpha, flavocytochrome b-558 alpha polypeptide, Neutrophil cytochrome b 22 kDa polypeptide, p22 phagocyte B-cytochrome, p22phox, p22-phox, Superoxide-generating NADPH oxidase light chain subunit|
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