Cytokeratin 1/10, Rabbit anti-Human,Mouse, Alexa Fluor 350, Clone: KRT10/1990R, Novus Biologicals™
Rabbit Monoclonal Antibody
Manufacturer: Novus Biologicals NBP275768AF350
DescriptionCytokeratin 1/10 Monoclonal antibody specifically detects Cytokeratin 1/10 in Human, Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin).
|Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin|
|50mM Sodium Borate with 0.05% Sodium Azide|
|Skin extract of a human Psoriasis patient|
|Protein A or G purified|
|Store at 4°C in the dark.|
|This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.|
|Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin)|
|Alexa Fluor 350|
|67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK|
|Cell Biology, Cellular Markers|
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