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Cytokeratin 1/10, Rabbit anti-Human,Mouse, DyLight 550, Clone: KRT10/1990R, Novus Biologicals™

Rabbit Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275768R

Catalog No. NB009049


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Description

Description

Cytokeratin 1/10 Monoclonal antibody specifically detects Cytokeratin 1/10 in Human, Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin).
Specifications

Specifications

Cytokeratin 1/10
KRT10/1990R
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
50mM Sodium Borate with 0.05% Sodium Azide
KRT10
Skin extract of a human Psoriasis patient
Monoclonal
Protein A or G purified
RUO
Store at 4°C in the dark.
This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin)
DyLight 550
Purified,Conjugated
67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK
Rabbit
IgG
Primary
0.1 mL
Cell Biology, Cellular Markers
Human,Mouse
SDS
Documents
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