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Thermo Scientific™ Lab Vision™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Thermo Scientific™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen Cytokeratin 16 Ab-1
Clone LL025
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS620P1
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Thermo Scientific™
MS620P1
Purified Ab with BSA and Azide 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS620R1
View Documents
Thermo Scientific™
MS620R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Thermo Scientific™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody.

Keratins 6 and 16 are expressed in keratinocytes that are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.

Host Species: Mouse

Clone: LL025

Isotype: IgG1

Species Reactivity: Human. Does not react with rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of human cytokeratin 16

Molecular Weight: 48 kDa

Positive Control: Squamous cell CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Cytokeratin 16 Ab-1
Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
RUO
Primary
IgG1
LL025
Monoclonal
Murine
Cytoskeletal Protein
A synthetic peptide from the C-terminus of human cytokeratin 16
SDS
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