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Epredia™ Lab Vision™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Epredia™ Cytokeratin 17 Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS489S1

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Catalog No. MS489S1


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Description

Description

The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life. Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin. Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC), suggesting that BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells.

Host Species: Mouse

Clone: E3

Isotype: IgG2b/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Cytokeratin preparation from rat enterocytes

Molecular Weight: 46 kDa

Positive Control: Squamous cell CA, Skin

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence
Specifications

Specifications

Cytokeratin 17 Ab-1
Monoclonal
Unconjugated
Keratin preparation from rat enterocytes
500 μL
Cytoskeletal Protein
Human, Rat
IgG2b κ
Immunofluorescence, Immunohistochemistry (Paraffin)
E3
Mouse
Squamous cell CA, skin
IVD
Primary
Concentrated
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