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Cytokeratin 17 Mouse, Clone: KRT17/778, Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

$574.00

Specifications

Antigen Cytokeratin 17
Clone KRT17/778
Concentration 1.0 mg/mL
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP247684A
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Novus Biologicals
NBP2476840.1MG
0.1 mg
Each for $574.00
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NBP247684B
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Novus Biologicals
NBP2476840.2MG
0.2 mg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

Cytokeratin 17 Monoclonal specifically detects Cytokeratin 17 in Human, Rat, Porcine, Bovine, Goat samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications

Specifications

Cytokeratin 17
1.0 mg/mL
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Unconjugated
Mouse
Cancer
PBS with No Preservative
3872
Recombinant full-length human KRT17 protein
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
46 kDa
KRT17/778
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Monoclonal
Purified
RUO
Human, Rat, Porcine, Goat, Primate
39.1, CK-17, cytokeratin-17, K17, keratin 17, keratin, type I cytoskeletal 17, keratin-17, PC, PC2, PCHC1
KRT17
IgG2b κ
Protein A or G purified
Cytokeratin 17 (CK17) is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glands such as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. The histologic differentiation of ampullary cancer, intestinal vs. pancreatobiliary, is very important for treatment. Usually anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
SDS
Product Certifications
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