Cytokeratin 5/6, Mouse anti-Human, Alexa Fluor 647, Clone: KRT5.6/3820, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP279842AF647

Catalog No. NB010870

Description

Cytokeratin 5/6 Monoclonal antibody specifically detects Cytokeratin 5/6 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

• Antigen: Cytokeratin 5/6
• Clone: KRT5.6/3820
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Format: Conjugated, Purified
• Gene Symbols: KRT5
• Immunogen: Recombinant full-length human Cytokeratin 5/6 protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Storage Requirements: Store at 4°C in the dark.
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
• Conjugate: Alexa Fluor 647
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Alias: 58 kDa cytokeratin, CK5, CK-5, cytokeratin-5, DDD, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, K5, keratin 5, keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockaynetypes), keratin, type II cytoskeletal 5, Keratin-5, KRT5A, Type-II keratin Kb5
• Host Species: Mouse
• Isotype: IgG1 Kappa
• Quantity: 0.1 mL
• Research Discipline: Cell Biology, Cellular Markers
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes polypeptides of 58kDa and 56kDa, identified as cytokeratin 5 and 6 respectively. It shows no reaction with keratin 1, 8, or 19. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheliod mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody in the identification of mesothelioma and lung squamous cell carcinoma.