Epredia™ Lab Vision™ Cytokeratin 5 Ab-1, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cytokeratin 5 Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1896S1

Catalog No. MS1896S1

Description

Twenty human keratins are divided into acidic (pI <5.7) and basic (pI >6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor identification. Point mutations in cytokeratin5 gene can cause various types of epidermolysis bullosa simplex. It is expressed in most epithelial and biphasic mesotheliomas.

Host Species: Mouse

Clone: XM26

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: C-terminal

Immunogen: Recombinant protein corresponding to C-terminal 103 aa of cytokeratin 5

Molecular Weight: 58 kDa

Positive Control: Mesothelioma

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: Cytokeratin 5 Ab-1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant protein corresponding to C-terminal 103 aa of cytokeratin 5
• Quantity: 500 μL
• Research Discipline: Cytoskeletal Protein
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: XM26
• Host Species: Mouse
• Purification Method: Mesothelioma
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Concentrated