Mouse anti-Cytokeratin, pan, Clone: KRTL/1077 + KRTH/1076, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2443670.02MG
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), ImmunofluorescenceCytokeratin, pan Monoclonal antibody specifically detects Cytokeratin, pan in Human, Rat samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
|KRTL/1077 + KRTH/1076|
|10mM PBS and 0.05% BSA with 0.05% Sodium Azide|
|Store at 4C.|
|Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence|
|Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 1 - 2 ug/ml|
|Recombinant human KRT77 and KRT76 protein|
|Protein A or G purified|
|Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.|
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