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CZC 54252 hydrochloride, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
1784253-05-9
C22H25ClN6O4S
504.99
CLGWUCNXOBLWFM-UHFFFAOYSA-N
czc 54252 hydrochloride,n-2-5-chloro-2-2-methoxy-4-morpholin-4-ylanilino pyrimidin-4-yl amino phenyl methanesulfonamide;hydrochloride,n-2-5-chloro-2-2-methoxy-4-4-morpholinyl phenyl amino-4-pyrimidinyl amino phenyl methanesulfonamide hydrochloride
44252734
CHEBI:78414
N-[2-[[5-chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide
COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl
This item is not returnable. View return policy
1784253-05-9
C22H25ClN6O4S
504.99
CLGWUCNXOBLWFM-UHFFFAOYSA-N
czc 54252 hydrochloride,n-2-5-chloro-2-2-methoxy-4-morpholin-4-ylanilino pyrimidin-4-yl amino phenyl methanesulfonamide;hydrochloride,n-2-5-chloro-2-2-methoxy-4-4-morpholinyl phenyl amino-4-pyrimidinyl amino phenyl methanesulfonamide hydrochloride
44252734
CHEBI:78414
N-[2-[[5-chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide
COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl

Potent LRRK2 inhibitor; neuroprotective

Potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC50 values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). Attenuates neuronal injury induced by LRRK2-G2019S mutant activity in primary human neurons (EC50 = 1 nM).
Quantity 50mg
Formula Weight 541.45
Percent Purity >98%
Chemical Name or Material CZC 54252 hydrochloride

Recommended Storage : Store at +4°C