DAF-3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA116925

Catalog No. 01-950-166

Description

Signals from TGF-beta superfamily receptors are transduced to the nucleus by Smad proteins, which transcriptionally activate target genes. In Caenorhabditis elegans (C.elegans), defects in a TGF-beta-related pathway cause a reversible developmental arrest and metabolic shift at the dauer larval stage. DAF-3 transgenes interfere with dauer formation, playing a role in the nucleus. DAF-3 is unique in that it is antagonized, rather than activated, by a TGF-beta pathway.

Specifications

• Antigen: DAF-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: daf-3
• Gene Alias: CELE_F25E2.5; daf-3; Dwarfin sma;MH2 domain-containing protein; protein-coding; Smad protein
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: C. elegans
• Product Type: Antibody
• Isotype: IgG

• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.05% sodium azide
• Gene Accession No.: 0
• Gene Symbols: daf-3
• Immunogen: Synthetic peptide between amino acids 700-796 of the C.elegans DAF-3 protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 180431
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid