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DAND5 Mouse anti-Human, Clone: OTI3A3, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503713

Catalog No. 50-167-4540


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Description

Description

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
Specifications

Specifications

DAND5
Monoclonal
Unconjugated
DAND5
Liquid
DAND5
Human recombit protein fragment corresponding to amino acids 23-189 of human DAND5 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunocytochemistry, Immunofluorescence
OTI3A3
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q8N907
CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, SP1
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
199699
Documents
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