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DAND5 Mouse anti-Human, Clone: OTI2H3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525684

Catalog No. PIMA525684


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Description

Description

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
Specifications

Specifications

DAND5
Monoclonal
1.04 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N907
Cerberus 2, Cerberus like-2, CKTSF1B3, DAND5, Dante, GREM3, CER2CRL2, cerberus-like 2, Cerberus-like protein 2, CERL2, Cerl-2, cerl-2, CKTSF1B3MGC126849, COCO, Cysteine knot superfamily 1, BMP antagonist 3, DAN domain family member 5, DAN domain family, member 5, DANTE, DTE, FLJ38607, GREM3cerberus 2, gremlin-3, Gremlin-3, SP1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
199699
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI2H3
Unconjugated
DAND5
Liquid
DAND5
Human recombit protein fragment corresponding to amino acids 23-189 of DAND5 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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