Invitrogen™ DAP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120841

Catalog No. PIPA5120841

Description

Positive test controls include: HeLa, 293T, Jurkat, LO2, Mouse brain. Immunogen sequence: PKTINQIRQD AVKDLGVFIP APMAQGMRSD FFLEGPFMPP RMKMDRDPLG GLADMFGQMP GSGIGTGPGV IQDRFSPTMG RHRSNQLFNG HGGHIMPPTQ SQFGEMGGKF MKSQGLSQLY HNQSQGLLSQ LQGQSKDMPP RFSKKGQLNA DEISLRPAQS FLMNKNQVPK L.

CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT). CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: DAP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Eif4g2
• Gene Alias: AA589388; AAG1; aging-associated protein 1; DAP5; DAP-5; Death-associated protein 5; E130105L11Rik; eIF4G 2; eIF-4G 2; EIF4G2; eif4g2.L; eif4g2.S; eIF-4-gamma 2; Eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4 gamma, 2; eukaryotic translation initiation factor 4 gamma, 2 L homeolog; eukaryotic translation initiation factor 4 gamma, 2 S homeolog; eukaryotic translation initiation factor 4 gamma, 2 S homeolog; eukaryotic translation initiation factor 4, gamma 2; eukaryotic translation initiation factor 4G-like 1; FLJ41344; NAT1; Natm1; Novel APOBEC-1 target 1; OK/SW-cl.75; p97; translation repressor NAT1; XELAEV_18024574mg
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13690, 1982, 361628
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: P78344, Q62448
• Gene Symbols: Eif4g2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 320-490 of human EIF4G2/p97 (NP_001409.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG