DAPK2 Mouse anti-Canine, Human, Non-human primate, Rat, Clone: OTI1C5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525084
DescriptionCalcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of maligt epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|DRAK2, DAP kinase-related apoptosis-inducing protein kinase 2, death-associated protein kinase-related 2, serine/threonine-protein kinase 17B|
|-20° C, Avoid Freeze/Thaw Cycles|
|23604, 300799, 610682, 706421|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Full length human recombit protein of DAPK2 produced in HEK293T cell|
|Canine, Human, Non-human primate, Rat|
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