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DAPK2 Mouse anti-Canine, Human, Non-human primate, Rat, Clone: OTI1C5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525084

Catalog No. PIMA525084


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Description

Description

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of maligt epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).
Specifications

Specifications

DAPK2
Monoclonal
0.76 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9UIK4
DRAK2, DAP kinase-related apoptosis-inducing protein kinase 2, death-associated protein kinase-related 2, serine/threonine-protein kinase 17B
Mouse
IgG3
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23604, 300799, 610682, 706421
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
OTI1C5
Unconjugated
DAPK2
Liquid
DAPK2
Full length human recombit protein of DAPK2 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Non-human primate, Rat
Documents
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