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DATF1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5122041

Encompass

Catalog No. PIPA5122041


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Description

Description

Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFkB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

DATF1
Polyclonal
Unconjugated
DIDO1
6720461J16Rik; BYE1; C20orf158; D130048F08Rik; DATF1; DATF-1; death associated transcription factor 1; death inducer-obliterator 1; death inducer-obliterator-2; death inducer-obliterator-3; death-associated transcription factor 1; Death-inducer obliterator 1; dido; Dido1; DIDO2; DIDO3; DIO1; DIO-1; dJ885L7.8; KIAA0333
Rabbit
Antigen affinity chromatography
RUO
11083
-20°C
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
500 μg/mL
PBS with 50% glycerol and 0.05% ProClin 300
Q9BTC0
DIDO1
Recombinant protein Death Inducer Obliterator 1. The antigen corresponds to amino acid range 258-455 of the target protein.
20 μL
Primary
Human
Antibody
IgG
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