DC-SIGNR/CD299/CLEC4M Antibody (16E7), Alexa Fluor™ 594 - Chimeric, Novus Biologicals™

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP252649AF594

Catalog No. NP22649A94

Description

DC-SIGNR/CD299/CLEC4M Monoclonal specifically detects DC-SIGNR/CD299/CLEC4M in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

Specifications

• Antigen: DC-SIGNR/CD299/CLEC4M
• Classification: Monoclonal
• Conjugate: Alexa Fluor 594
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: CLEC4M
• Immunogen: CD299
• Primary or Secondary: Primary
• Test Specificity: Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
• Clone: 160000000
• Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunofluorescence
• Gene Alias: CD209L1, CD209Ldendritic cell-specific ICAM-3-grabbing nonintegrin 2, CD299, CD299 antigenMGC129964, C-type lectin domain family 4, member M, DC-SIGN2CD209 antigen-like protein 1, DC-SIGNRDC-SIGN-related protein, DCSIGNRMGC47866, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, HP10347, liver/lymph node-specific ICAM-3 grabbing non-integrin, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN, LSIGNC-type lectin domain family 4 member M, mannose binding C-type lectin DC-SIGNR
• Host Species: Rabbit
• Quantity: 0.1 mL
• Gene ID (Entrez): 10332
• Target Species: Human
• Isotype: IgG κ