DC-SIGNR/CD299/CLEC4M Rabbit anti-Human, Alexa Fluor 532, Clone: 160000000, Novus Biologicals
Rabbit Monoclonal Antibody
Manufacturer: Novus Biologicals NBP252649AF532
DescriptionDC-SIGNR/CD299/CLEC4M Monoclonal antibody specifically detects DC-SIGNR/CD299/CLEC4M in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence.
|Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence|
|Protein A or G purified|
|Adaptive Immunity, Immunology, Signal Transduction, Virology Bacteria and Parasites|
|Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot|
|Alexa Fluor™ 532|
|50 mM sodium borate with 0.05% sodium azide|
|CD209L1, CD209Ldendritic cell-specific ICAM-3-grabbing nonintegrin 2, CD299, CD299 antigenMGC129964, C-type lectin domain family 4, member M, DC-SIGN2CD209 antigen-like protein 1, DC-SIGNRDC-SIGN-related protein, DCSIGNRMGC47866, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, HP10347, liver/lymph node-specific ICAM-3 grabbing non-integrin, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN, LSIGNC-type lectin domain family 4 member M, mannose binding C-type lectin DC-SIGNR|
|Store at 4°C in the dark.|
|Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.|
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