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DC-SIGNR/CD299/CLEC4M Rabbit anti-Human, Alexa Fluor™ 750, Clone: 160000000, Novus Biologicals™

Rabbit Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP252649AF750

Catalog No. NP22649A70


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Description

Description

DC-SIGNR/CD299/CLEC4M Monoclonal antibody specifically detects DC-SIGNR/CD299/CLEC4M in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence.
Specifications

Specifications

DC-SIGNR/CD299/CLEC4M
160000000
Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence
Conjugated, Purified
CLEC4M
CD299
Protein A or G purified
Adaptive Immunity, Immunology, Signal Transduction, Virology Bacteria and Parasites
Primary
10332.0
Human
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Alexa Fluor™ 750
50 mM sodium borate with 0.05% sodium azide
CD209L1, CD209Ldendritic cell-specific ICAM-3-grabbing nonintegrin 2, CD299, CD299 antigenMGC129964, C-type lectin domain family 4, member M, DC-SIGN2CD209 antigen-like protein 1, DC-SIGNRDC-SIGN-related protein, DCSIGNRMGC47866, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, HP10347, liver/lymph node-specific ICAM-3 grabbing non-integrin, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN, LSIGNC-type lectin domain family 4 member M, mannose binding C-type lectin DC-SIGNR
Rabbit
IgG Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
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