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DCK Mouse anti-Human, Mouse, Rat, Clone: GT10412, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527740

Catalog No. PIMA527740


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Description

Description

Positive Control: A431, HeLa, HepG2, 293T, A549, H1299, HCT116, Neuro 2A, C8D30, NIH-3T3, Raw264.7, PC-12, Rat2 Predicted Reactivity: Rhesus Monkey (96%), Bovine (95%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

DCK (Deoxycytidine kinase) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Specifications

Specifications

DCK
Monoclonal
2.01 mg/ml
PBS with no preservative
P27707, P43346, P48769
deoxycytidine kinase
Mouse
IgG2b
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
13178, 1633, 79127
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
GT10412
Unconjugated
DCK
Liquid
Dck
Recombit protein encompassing a sequence within the center region of human DCK. The exact sequence is proprietary.
Protein A
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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