DCK Mouse anti-Human, Clone: OTI16G6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525502
DescriptionDeoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Deoxycytidine kinase; dCK|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of DCK produced in HEK293T cell|
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