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DCK Mouse anti-Human, Clone: OTI3F5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525500

Catalog No. PIMA525500


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Description

Description

Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.
Specifications

Specifications

DCK
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P27707
Deoxycytidine kinase; dCK
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1633
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI3F5
Unconjugated
DCK
Liquid
DCK
Full length human recombit protein of DCK produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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