DCX Mouse anti-Human, Clone: OTI4A3, liquid, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene TA501778

Catalog No. 50-167-2897

Description

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

Specifications

• Antigen: DCX
• Classification: Monoclonal
• Concentration: 0.73 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O43602
• Gene Alias: DBCN, DC, LISX, SCLH, XLIS
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 1641

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI4A3
• Conjugate: Unconjugated
• Gene: DCX
• Format: Liquid
• Gene Symbols: DCX
• Immunogen: Full length human recombit protein of human DCX produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human