Tocris™ DDR1-IN-1 dihydrochloride

Selective DDR1 inhibitor

Manufacturer: Tocris™ 5077/10

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Catalog No. 50-771-0

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For Research Use Only


    Product Type DDR1-IN-1 dihydrochloride
    Inhibitors DDR1-IN-1 dihydrochloride
    Purity >98
    Molecular Weight 625.51
    Quantity 10mg

    Selective discoidin domain receptor 1 (DDR1) tyrosine kinase inhibitor (IC50 values are 105 and 413nM for DDR1 and DDR2 respectively). Inhibits integrin-induced DDR1 autophosphorylation in an osteosarcoma cell line.

    • Chemical Name: N-[3-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)oxy]-4-methylphenyl]-4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzamide dihydrochloride
    • Formula: C30H31F3N4O3.2HCl
    • Solubility: Soluble to 100mM in water and to 50mM in DMSO
    • Purity: >98

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