Bachem Decanoyl-Arg-Val-Lys-Arg-chloromethylketone, 5mg, 150113-99-8, MFCD00798792, Trifluoroacetate salt
Manufacturer: Bachem 4026850.0005
Dec-RVKR-CMK binds to the catalytic site of furin and therefore acts as a potent inhibitor of cleavage and fusion activity of viral glycoproteins, as well as virus replication. Furthermore, it was demonstrated that Dec-RVKR-CMK decreased the production of β-amyloid-induced active matrix metalloproteinase 2 in U87 cells. Apart from furin, N-1505 also inhibited the proprotein convertases PC7/LPC, PACE4, and PC6 (W.Garten, personal communication).
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