Invitrogen™ DEDD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578280

Catalog No. PIPA578280

Description

Positive Control: mouse leukocyte treated with CFA Predicted Reactivity: Rat (98%), Xenopus laevis (86%), Rhesus Monkey (99%), Bovine (97%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: DEDD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEDD
• Gene Alias: CASP8IP1; death effector domain containing; death effector domain-containing; death effector domain-containing protein; Death effector domain-containing testicular molecule; DEDD; DEDD1; Dedpro1; DEFT; FLDED1; FLDED-1; KE05; tumor necrosis factor (ligand) superfamily, member 19
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21945, 9191
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O75618, Q9Z1L3
• Gene Symbols: DEDD
• Immunogen: Recombinant protein encompassing a sequence within the center region of human DEDD. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG