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Desmin Antibody (DES/1711), Alexa Fluor™ 750, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP254503AF750
Description
Desmin Monoclonal specifically detects Desmin in Human, Mouse, Rat, Chicken, Hamster samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.Specifications
Desmin | |
Monoclonal | |
Alexa Fluor 750 | |
50 mM sodium borate with 0.05% sodium azide | |
DES | |
Recombinant human desmin protein (Uniprot: P17661) | |
Primary | |
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. | |
Store at 4°C in the dark. |
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
DES/1711 | |
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin | |
CMD1IFLJ41013, CSM1, CSM2, desmin, FLJ12025, FLJ39719, FLJ41793, intermediate filament protein | |
Mouse | |
0.1 mL | |
1674 | |
Human, Mouse, Rat, Chicken, Hamster | |
IgG1 κ |
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