BioVision Inc Deubiquitinase Activity Assay Kit (Fluorometric): Deubiquitinase Activity Assay Kit (Fluorometric): Convenient and Highly Sensitive Assay to Measure DUB Activity in Cells, Tissues, purified enzyme, etc. within 30 min. 100 Assays
Manufacturer: BioVision Inc K485100
Deubiquitinase Activity Assay Kit (Fluorometric): Cell activity and viability is tightly regulated by controlling the production and degradation of the thousands of different proteins in the cell. The proteasome is responsible for the majority of cellular protein degradation; however, drugs targeting the proteasome can have side effects caused by the lack of specificity associated with inhibiting the proteasome itself. The enzymes responsible for cleavage, and hence removal of ubiquitin from ubiquitinated proteins, are known as de-ubiquitinating enzymes, or DUBs. By removing the ubiquitin molecule, the protein escapes the fate of proteasomal degradation and remains a viable factor in the cell. BioVision's Deubiquitinase Activity Assay Kit provides a straight-forward and general measure of deubiquitinase activity by utilizing a fluorescent deubiquitinase substrate to detect activity as low as 0.25 µU with purified enzyme. BioVision charges an Ice pack fee for each order.