Invitrogen™ DGKB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109630

Catalog No. PIPA5109630

Description

Immunogen sequence: LMKILKDIEN STEIMLDRWK FEVIPNDKDE KGDPVPYSII NNYFSIGVDA SIAHRFHIMR EKHPEKFNSR MKNKFWYFEF GTSETFSATC KKLHESVEIE CDGVQIDLIN ISLEGIAILN IPSMHGGSNL WGESKKRRSH RRIEKKGSDK RTTVTDAKEL KFASQDLSDQ LLEVVGLEGA MEMGQIYTGL KSAGRRLAQC SCVVIRTSKS LPMQIDGEPW MQTPCTVSTE.

Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified.

Specifications

• Antigen: DGKB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DGKB
• Gene Alias: 6430574F24; 90 kDa diacylglycerol kinase; 90kda; C630029D13Rik; DAG kinase beta; Dagk; DAGK2; DGK; Dgkb; DGK-beta; Diacylglycerol kinase 90kDa; diacylglycerol kinase beta; diacylglycerol kinase beta, 90kDa; diacylglycerol kinase, beta; diacylglycerol kinase, beta 90kDa; diglyceride kinase beta; Kiaa0718; mKIAA0718
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 217480, 54248
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P49621, Q6NS52
• Gene Symbols: DGKB
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 544-773 of human DGKB (NP_663733.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG