DHRS4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA587775

Catalog No. PIPA587775

Description

Immunogen sequence: MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL; Positive Samples: HeLa, LO2, A-549, MCF-7, SW620, Mouse liver, Mouse lung, Mouse intestine, Rat liver; Cellular Location: Nucleus, Peroxisome

Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.

Specifications

• Antigen: DHRS4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DHRS4
• Gene Alias: AI043103, AI790593, carbonyl reductase, CR, D14Ucla2, DCR-AKL, dehydrogenase/reductase (SDR family) member 4, dehydrogenase/reductase (SDR family) member 4 like 2A, dehydrogenase/reductase 4, dehydrogenase/reductase SDR family member 4, DHRS4, mouNRDR, NADH-dependent retinal reductase, NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase, NADPH-dependent retinol dehydrogenase/reductase, NADP-retinol dehydrogenase, NDRD, NDRD protein, NRDR, Peroxisomal short-chain alcohol dehydrogenase, PH PSCD, PHCR, PSCD, rabNRDR, RRD, SCAD-SRL, SDR25C1, SDR25C2, SDR-SRL, Short chain dehydrogenase/reductase family 25C member 2, short chain dehydrogenase/reductase family 25C, member 1, short chain dehydrogenase/reductase family 25C, member 2, short-chain dehydrogenase/reductase family member 4, UNQ851/PRO1800
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10901, 266686, 28200
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 2.24 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
• Gene Accession No.: Q8VID1, Q99LB2, Q9BTZ2
• Gene Symbols: DHRS4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human DHRS4 (NP_0662842)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov