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Di-Methyl-Acetyl-Histone H3 (Arg17, Lys18) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540094

Catalog No. PA540094


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Description

Description

Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called ""histone code"". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.
Specifications

Specifications

Di-Methyl-Acetyl-Histone H3 (Arg17, Lys18)
Polyclonal
Unconjugated
HIST1H3A
Liquid
H3c1, HIST1H3A
KLH-conjugated synthetic peptide corresponding to the region of human histone H3 containing the asymmetrically dimethylated R17 and the acetylated lysine 18 (H3R17me2(asym).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
ChIP assay, ChIP-sequencing, ELISA, Immunocytochemistry, Immunofluorescence, Peptide Array, Western Blot
0.94 mg/mL
PBS with 0.05% Proclin 300, 0.05% sodium azide; pH 7.4
P68431, P68433
H3R17me2(asym)K18ac, H3R17me2K18ac, Histone H3, Histone 1, H3a, Histone H3.1, histone H3/a, HIST1H3A
Rabbit
IgG
50 μg
-20°C or -80°C if preferred
Primary
360198, 8350
Documents
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