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Di-Methyl-Histone H3 (Lys79) Rabbit anti-Human, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen 701770

Catalog No. PI701770


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Description

Description

This antibody is predicted to react with Rat, Bat, Cat and Pig Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post tranlationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Specifications

Specifications

Di-Methyl-Histone H3 (Lys79)
Recombinant Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P68431
Histone Cluster 1, H3a
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage
Primary
8350
ChIP assay, Immunocytochemistry, Immunofluorescence
21H23L16
Unconjugated
HIST1H3A
Liquid
HIST1H3A
Peptide corresponding to Human HIST1H3A (aa 76-84 )
Protein A
RUO
Antibody
Monoclonal
Human
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