Dicer Mouse anti-Human, Clone: GT1176, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527827
Positive Control: A431 Predicted Reactivity: Mouse (97%), Zebrafish (93%), Xenopus laevis (92%), Pig (99%), Chicken (96%), Rhesus Monkey (100%), Bovine (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.DICER1 is a ribonuclease that has been extensively shown to be related to cancer. Small interfering RNAs are generated through DICER, and seem to play important roles in mitosis in normal cells and oncogenesis in mutated cells. DICER1 mutations are associated with blastoma, breast cancer, adenocarcinoma, and pancreatitis. In vision and hearing, DICER1 has been implicated in serious microRNA induced malformations of critical sensory cells. DICER1 is important in myelination and other nervous system protections. Finally, DICER1 is related to cardiovascular diseases, since microRNAs are aberrantly expressed in some pathological conditions.
|PBS with no preservative|
|DCR1, DICER1, Dicer, HERNA, MNG1, dicer 1 ribonuclease III|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Recombit protein encompassing a sequence within the aa 819-1112 of Human Dicer. The exact sequence is proprietary.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok