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  7. Dimebon dihydrochloride, Tocris Bioscience™

Dimebon dihydrochloride, Tocris Bioscience™

Catalog Number 32011
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
97657-92-6
C21H27Cl2N3
392.368
GTWLIQOLGOZTLF-UHFFFAOYSA-N
dimebon dihydrochloride, dimebolin dihydrochloride, latrepirdine dihydrochloride, unii-8b9414qq5m, latrepirdine dihydrochloride usan, 2,8-dimethyl-5-2-6-methylpyridin-3-yl ethyl-2,3,4,5-tetrahydro-1h-pyrido 4,3-b indole dihydrochloride, dimebone dihydrochloride hydrate, dimebolin dihydrochloride hydrate
23729232
2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;dihydrochloride
CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl
This item is not returnable. View return policy
97657-92-6
C21H27Cl2N3
392.368
GTWLIQOLGOZTLF-UHFFFAOYSA-N
dimebon dihydrochloride, dimebolin dihydrochloride, latrepirdine dihydrochloride, unii-8b9414qq5m, latrepirdine dihydrochloride usan, 2,8-dimethyl-5-2-6-methylpyridin-3-yl ethyl-2,3,4,5-tetrahydro-1h-pyrido 4,3-b indole dihydrochloride, dimebone dihydrochloride hydrate, dimebolin dihydrochloride hydrate
23729232
2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;dihydrochloride
CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl

Description

Neuroprotectant; protects against β-amyloid neurotoxicity

Non-selective antihistamine that displays cognitive enhancing abilities. Also displays high affinity for 5-HT (particularly 5-HT6 and 5-HT7), α-adrenergic, dopaminergic, AMPA and NMDA receptors, and L-type calcium channels. Does not inhibit acetylcholinesterase activity. Exhibits neuroprotective activity in cellular models of Alzheimer's and Huntington's disease and preserves cognitive function following administration to AF64A lesioned rats. Protects neurons against the neurotoxic action of β-amyloid fragment; shown to enhance autophagy in yeast and reduce intracellular Aβ42 levels.
Quantity 1 mg
Formula Weight 392.37
Percent Purity >98%
Chemical Name or Material Dimebon dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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