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Corning™ Dissolvable Microcarriers

Corning™ Dissolvable Microcarriers are designed to simplify cell harvest, separation and concentration processes and are ideal for bioprocess scale-up.

Manufacturer:  Corning™ 4990

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Catalog No. 07-201-123

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  • Offer cell separations that are faster, gentler, and more convenient than other standard commercially available microcarriers
  • Comprised of polygalacturonic acid (PGA) polymer chains cross linked via calcium ions pre-coated with either denatured collagen or Corning Synthemax™ II to enhance cell attachment for optimal yield and viability
  • Dissolvable within 10 to 20 minutes using EDTA and pectinase for easy separation of cells from the actual microcarriers
  • Narrow size distribution (1.02-1.03 g/cm3 density, 200-300µm fully hydrated) and large surface area (5000cm2/g) result in a more homogenous culture
  • Optical clarity for visualizing cell morphology
  • Presterilized to Sterility Assurance Level (SAL) of 10-6
  • Nonpyrogenic
  • Applications areas include cell therapy, vaccine production or large-volume adherent cell culture scale-up and cell banking


Corning™ Synthemax II
Large-volume adherent cell culture scale-up and cell banking
Polygalacturonic acid (PGA) polymer chains cross linked via calcium ions
Dissolvable microcarrier
200-300μm fully hydrated
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