Invitrogen™ DLC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529784

Catalog No. PIPA529784

Description

Recommended positive controls: A549, HepG2. Predicted reactivity: Mouse (94%), Rat (93%), Dog (97%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

Specifications

• Antigen: DLC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dlc1
• Gene Alias: A730069N07Rik; ARHGAP 7; ARHGAP7; deleted in liver cancer 1; deleted in liver cancer 1 protein; Deleted in liver cancer 1 protein homolog; deleted in liver cancer 1 variant 2; deleted in liver cancer variant 4; DLC 1; DLC1; Dlc-1; DLC1 Rho GTPase activating protein; DLC1 Rho GTPase activating protein; rho GTPase-activating protein 7; FLJ21120; HP; HP protein; KIAA1723; p122 RhoGAP; p122-RhoGAP; rho GTPase activating protein 7; rho GTPase-activating protein 7; RhoGAP; Rho-GTPase-activating protein 7; rho-type GTPase-activating protein 7; STARD 12; STARD12; StAR-related lipid; StAR-related lipid transfer (START) domain containing 12; stAR-related lipid transfer protein 12; START domain-containing protein 12; transfer protein 12; unm_sa1141
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10395, 50768
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96QB1, Q9R0Z9
• Gene Symbols: Dlc1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1271 and 1528 of Human DLC1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov