Invitrogen™ DLC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120668

Catalog No. PIPA5120668

Description

Positive test controls include: Mouse lung. The target is usually found in the following locations: Cell junction, Cytoplasm, Membrane, Peripheral membrane protein, focal adhesion. Immunogen sequence: DAPKVNAVDT LNVKDIAPEK QLLNSAVIAQ QRRKPDPPKD ENERSTCNVV QNEFLDTPCT NRGLPLLKTD FGSCLLQPPS CPNGMSAENG LEKSGFSQHQ NKSPPKVKAE DGMQCLQLKE TLATQEPTDN QVRLRKRKEI REDRDRARLD SMVLLIMKLD QLDQDIENAL STSSSPSGTP TNLRRHVPDL ESGSESGADT ISVNQTRVNL SSDTESTDLP SSTPVANSGT KPKTTAIQGI SEKEKAGKLT FWFCFLANLF.

This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

Specifications

• Antigen: DLC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dlc1
• Gene Alias: A730069N07Rik; ARHGAP 7; ARHGAP7; deleted in liver cancer 1; deleted in liver cancer 1 protein; Deleted in liver cancer 1 protein homolog; deleted in liver cancer 1 variant 2; deleted in liver cancer variant 4; DLC 1; DLC1; Dlc-1; DLC1 Rho GTPase activating protein; DLC1 Rho GTPase activating protein; rho GTPase-activating protein 7; FLJ21120; HP; HP protein; KIAA1723; p122 RhoGAP; p122-RhoGAP; rho GTPase activating protein 7; rho GTPase-activating protein 7; RhoGAP; Rho-GTPase-activating protein 7; rho-type GTPase-activating protein 7; STARD 12; STARD12; StAR-related lipid; StAR-related lipid transfer (START) domain containing 12; stAR-related lipid transfer protein 12; START domain-containing protein 12; transfer protein 12; unm_sa1141
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50768, 58834
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.58 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q63744, Q9R0Z9
• Gene Symbols: Dlc1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of human DLC1 (NP_079043.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG