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Tocris Bioscience™ DMH2 Available on GSA/VA Contract for Federal Government customers only.

Type I BMP receptor inhibitor

$209.00 - $869.50


Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
558050 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
5580/50
Each for $869.50
Add to cart
 
558010 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
5580/10
Each for $209.00
Add to cart
 
Description

Description

Type I BMP receptor inhibitor (Ki values are <1, 5.4 and 43 nM for ALK6, ALK3 and ALK2, respectively). Exhibits >30-fold selectivity over ALK4, ALK5, BMPR2, AMPK and VEGFR2. Also binds to TGFBR2 (Ki = 85 nM). Decreases growth and induces cell death of H1299 non-small cell lung carcinoma cells in vitro. Enhances liver regeneration in vivo.

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