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POLD3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550951

Catalog No. PA550951


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Description

Description

DNA pol δ3 Polyclonal Antibody detects endogenous levels of DNA pol δ3 protein.

DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol alpha, beta, delta and epsilon. DNA pol delta and DNA pol epsilon are multisubunit enzymes, with DNA pol delta consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol delta 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol delta.
Specifications

Specifications

POLD3
Polyclonal
Unconjugated
POLD3
Liquid
POLD3
Synthesized peptide derived from the C-terminal region of human DNA pol delta3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q15054, Q9EQ28
POLD3, KIAA0039, DNA polymerase delta subunit 3, DNA polymerase delta subunit p66
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10714, 293144, 67967
Documents
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