DNA polymerase beta Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 180031AP
DescriptionDNA polymerase beta comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase beta, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N ft.-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates beta-pol level. DNA polymerase beta fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.
|DNA polymerase beta|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P06746, P06766, Q8K409|
|DNA polymerase beta, POLB|
|18970, 29240, 5423|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|DNA polymerase beta Fusion Protein Ag12496|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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