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DNA polymerase beta Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 180031AP

Catalog No. 50-173-1929


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Description

Description

DNA polymerase beta comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase beta, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N ft.-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates beta-pol level. DNA polymerase beta fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.
Specifications

Specifications

DNA polymerase beta
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P06746, P06766, Q8K409
DNA polymerase beta, POLB
Rabbit
IgG
150 μL
-20°C
Primary
18970, 29240, 5423
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
POLB
Liquid
Polb
DNA polymerase beta Fusion Protein Ag12496
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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