DNAJB2 Monoclonal Antibody (OTI5E5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA502263

Catalog No. 50-167-3334

Description

The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.

Specifications

• Antigen: DNAJB2
• Classification: Monoclonal
• Concentration: 0.48 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P25686
• Gene Symbols: DNAJB2
• Immunogen: Full length human recombit protein of human DNAJB2 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: OTI5E5
• Conjugate: Unconjugated
• Gene: DNAJB2
• Gene Alias: CMT2T, DSMA5, HSJ-1, HSJ1, HSPF3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3300
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid